Union pretty well falls down on the job once you cross Broadway. Where are you trying to get to on 22nd? My autopilot goes Denny -> Boren -> James (morphs into) Cherry -> home. But if you were, say, trying to get to Seattle Kajukenbo, I might go Denny -> Boren -> Pike -> Broadway -> Union. Or investigate whether it's Pike or Pine that goes through Madison nicely, and take that one all the way to 22nd.

Or just use a better map/website....